Historical Perspective: Gut Dysbiosis and Hypertension Honorary Senior Research Associate
نویسندگان
چکیده
Physiological Genomics PG-00063-2015 R1 2 3 4 Historical perspective: Gut dysbiosis and hypertension 5 6 7 John William Honour PhD 8 Honorary Senior Research Associate 9 Institute for Women's Health 10 University College London 11 Huntley ST 12 London WC1E 6AU 13 UK 14 15 Running head : Gut dysbiosis and hypertension 16 17 Word count: Text 1795 words, 2956 inc refs ; 1 Figure 18 19 Reprint requests to John W Honour PhD, John William Honour PhD, Honorary 20 Senior Research Associate, Institute for Women's Health, University College 21 London, Huntley ST, London WC1E 6AU, UK. E-mail [email protected] 22 23 24 25 26 27 28 Articles in PresS. Physiol Genomics (July 21, 2015). doi:10.1152/physiolgenomics.00063.2015
منابع مشابه
CALL FOR PAPERS Gut Microbiota in Health and Disease Historical perspective: gut dysbiosis and hypertension
AN ENORMOUS NUMBER OF MICROBES populate external and internal surfaces of humans influencing a variety of aspects of host physiology such as providing nutrients and vitamins. The microbiome influences Phase I and Phase II drug metabolism (43) . In recent years, a number of studies have pointed to links between the gut microbiota and pathophysiology of diabetes (8, 36), cancer (27), bowel disord...
متن کاملBridging the Gap between Gut Microbial Dysbiosis and Cardiovascular Diseases
The human gut is heavily colonized by a community of microbiota, primarily bacteria, that exists in a symbiotic relationship with the host and plays a critical role in maintaining host homeostasis. The consumption of a high-fat (HF) diet has been shown to induce gut dysbiosis and reduce intestinal integrity. Recent studies have revealed that dysbiosis contributes to the progression of cardiovas...
متن کاملHypertension-Linked Pathophysiological Alterations in the Gut.
RATIONALE Sympathetic nervous system control of inflammation plays a central role in hypertension. The gut receives significant sympathetic innervation, is densely populated with a diverse microbial ecosystem, and contains immune cells that greatly impact overall inflammatory homeostasis. Despite this uniqueness, little is known about the involvement of the gut in hypertension. OBJECTIVE Test...
متن کاملGut dysbiosis is linked to hypertension.
Emerging evidence suggests that gut microbiota is critical in the maintenance of physiological homeostasis. This study was designed to test the hypothesis that dysbiosis in gut microbiota is associated with hypertension because genetic, environmental, and dietary factors profoundly influence both gut microbiota and blood pressure. Bacterial DNA from fecal samples of 2 rat models of hypertension...
متن کاملThe gut microbiome and hypertension.
PURPOSE OF REVIEW The mammalian mucosal surfaces are densely inhabited by a diverse microbial ecosystem termed the microbiota. Among these highly heterogeneous populations, the largest and richest is the gut microbiota, recently suggested to affect various physiological traits and susceptibility to disease. Novel metagenomic and metabolomic approaches, which have been developed in the past deca...
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